TWO YEARS AFTER... WHERE WE ARE ?

We are operating in the market of IVF Units for two years, what changed, what happened, which are our strengths - WHERE WE ARE ??

One in six couples worldwide experience some form of infertility problem at least once during their reproductive lifetime. The current prevalence of infertility lasting for at least 12 months is estimated to be around 9% worldwide for women aged 20-44.

20-30% of infertility cases are explained by physiological causes in men, 20-35% by physiological causes in women, and 25-40% of cases are because of a problem in both partners. In 10-20% οf case no cause is found. Infertility is also associated with lifestyle factors such as smoking, body-weight and stress. Increasing age in the female partner is one of the most common explanations today.

It is now estimated that more than 5 million babies have been born worldwide since the first IVF baby was born in 1978.Most ART treatments take place in women aged between 30 and 39.

Cycles/treatments

Europe leads the world in ART, initiating approximately 55% of all reported ART cycles.

In 2011, the latest year for which figures are available, 588,629 treatment cycles were reported from 33 European countries. This compares globally (in 2011) with 151,923 cycles from the US and 66,347 from Australia and New Zealand. The number of cycles performed in many developed countries has grown by 5-10% per annum over the last few years, but that growth is now slowing down.

In 2011 France had 85,433 cycles, Germany 67,596, Italy 63,777, Russia 56,253, Spain 66,120 and the UK 59,807. These were Europe's most active countries. In the Nordic countries, Sweden leads the table with 18,510 cycles, followed by Denmark 14,578. In Greece we have 55 registered IVF Units with estimated more than 10,000 cycles. The most active countries in the world are Japan and the USA.

Availability of ART

The Nordic countries and Belgium (but also Iceland and Slovenia) have the highest ART availability in terms of cycles per million population.

In Belgium, the Czech Republic, Denmark, Estonia, Iceland, Norway, Slovenia and Sweden more than 3.0% of all babies born were conceived by ART. By contrast the proportion in the USA - with 61,610 ART babies born - was estimated to be slightly more than 1% of total births.

Around 1.5 million ART cycles are performed each year worldwide, with an estimated 350,000 babies born.

Treatments

The most common fertilization (treatment) technique is ICSI. Overall, ICSI accounts for around two-thirds of all treatments worldwide, and conventional IVF around one-third. Success rates from frozen embryo transfer are increasing, as are the number of FER cycles. Vitrification, as an efficient cryopreservation technique, has improved the outcome of both embryo and oocyte freezing.

Ovarian hyper-stimulation syndrome (OHSS) is a complication related to ART. In 2011 there were 1683 OHSS cases recorded in 28 out of 33 European countries reporting to ESHRE, making up 0.6% of cycles. Russia (520), Italy (189) and Spain (184) reported the highest number of patients with OHSS.

Pregnancies and delivery rates

An analysis of world data for 2006 put average delivery rate from ART treatment at 20.5% per aspiration and 25.2% cumulative from a single started treatment cycle. The overall average number is 1.75 embryos per transfer.

In Europe the multiple delivery rate has declined steadily since 2000 from 26.9% to 19.4% in 2011 compared to a multiple delivery rate of 30% in the US (27.5% twin, 2.5% triplet or more deliveries).

Sweden has the lowest multiple delivery rate in the world. In 74.7% of all cases a single embryo was transferred.

There are different ways to measure the success of treatment. For example you can look at how likely a treatment cycle will lead to an ongoing pregnancy or live birth, or how likely each embryo that is transferred during treatment will lead to an ongoing pregnancy or live birth. This takes into account how many embryos a doctor can transfer in their cycles (eg, cycles can either have one, two or, very occasionally, three embryos transferred). 'Live birth per cycle started’ does not take into account that unfortunately some cycles are cancelled before the embryo transfer stage due to egg or embryo collection procedure or total freezing strategy and therefore cannot result in a live birth.

In this point we would proudly announce that Assisting Nature Assisted Reproduction Unit is one of the leading fertility Clinics in Europe assisting couples making their dream come true.

Our Clinic has an operating model supporting individually all patients via a monitoring group that has developed strong relationships between staff and patients.

During these two year we introduced a 60% non paper strategy in our Unit.

Our high ended Embryological Laboratory operate in class I Clean Room environment using IVF Witnessing for all procedures. 

During two years of working we haven't had any serious medical complication.

On the contrary during our detailed preoperative preparation process we diagnosed some cardio/hypertension  diseases and helped our patients  treat them.     

Assisting Nature IVF Unit is a pure "non OHSS Clinic", and we haven't had any case of hyper-stimulation due to our innovative " GnRh triggering / freeze all " policy. We develop the program of OncoFertility as well as Social Freezing helping patients in difficult stages of their life.

We consequently building "assisting nature ovum bank®" improving our market place in donation.

At the moment over 15% of our patients is involved in a PGS/CGH screening program.

We seriously develop and maintain the strategy "Advanced office hysteroscopy for all reproductive patients ® " rising our results higher.

With great respect we introduce the modern techniques in the field of male infertility, using our new acquisition  the Müller Microscope and perform the microTESE in home.

Together with our non profit Foundation " Assisting Nature College of Reproduction we organized already in 2015 two scientific event's, one Symposium " Innovation in male infertility " with Prof.Esteves S. end Prof.Sofikitis N. making a presentation on and " Preceptorship in reproductive endoscopy " in which we had the opportunity to host distinguished colleagues, Reproductive Specialists from Cairo, Egypt and exchange our experiences with them.



to be continued,  read our blog in few days............